名稱 | APC p.Q1429* Reference Standard |
型號(hào) | CBP10231 |
報(bào)價(jià) | ![]() |
特點(diǎn) | APC p.Q1429* Reference Standard |
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10231APC p.Q1429* Reference Standard

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CBP10231 | |
Format | Genomic DNA |
Description | APC Q1429* results in a premature truncation of the Apc protein at amino acid 1429 of 2843 within the Ctnnb1 binding and down-regulation domain of the Apc protein (PMID: 14672538). Q1429* has not been characterized, however Apc truncation mutants downstream of Q1429 are inactivating (PMID: 18199528) thus, Q1429* is predicted to lead to a loss of Apc protein function. |
Technical Data | |
DNA Change | c.4285C>T |
AA Change | p.Q1429* |
Mutation type | Substitution - Nonsense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000457016 |
Cosmic ID | COSM18836 |
Chr position(GRCh37) | chr5:112175576 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |