名稱(chēng) | U2AF1 p.Q157P Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10222 |
報(bào)價(jià) | ![]() |
特點(diǎn) | U2AF1 p.Q157P Reference Standard |
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電話(huà):4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10222U2AF1 p.Q157P Reference Standard 標(biāo)準(zhǔn)品

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CBP10222 | |
Format | Genomic DNA |
Description | U2AF1 Q157P is a hotspot mutation (PMID: 28986033) that lies within the C3H1-type 2 Zinc finger region of the U2af1 protein (UniProt.org). Q157P confers a gain of function to the U2af1 protein as indicated by increased exon skipping and aberrant splicing of U2af1 target genes in cell culture (PMID: 25267526, PMID: 25311244). |
Technical Data | |
DNA Change | c.470A>C |
AA Change | p.Q157P |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 33.33% |
Transcript | ENST00000291552 |
Cosmic ID | COSM211534 |
Chr position(GRCh37) | chr21:44514777 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |